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Translation

Grossly simplified, translation is the process by which RNA is read and specific amino acids are put together in order to form a protein. This progression is mediated by ribosomes essentially reading mRNA which encodes the correct order of amino acids for a particular protein. tRNA molecules attach to amino acids and transfer them into the ribosome for protein synthesis. Anti- translation antibodies can bind to ribosomal proteins or specific translation factors to facilitate, block, or otherwise change the process of RNA translation. These translation antibodies are useful in numerous avenues of research involving protein synthesis and immunoprecipitation.

Anti- frizzled 4 antibody targets a receptor or Wnt proteins known as a frizzled receptor. The receptor is thought to be modulated by G-protein type mechanism and facilitates the activation of Wnt target genes which play an integral role in retinal vascularization. Defects in frizzled 4 (FZD4) cause EVR1 (vitreoretinopathy exudative type 1). This disease is characterized by an avascular peripheral retina caused by the sudden stop in the growth of peripheral capillaries in the eye. Anti- TOX3 antibody targets the TOX3 protein which functions in the modification of chromatin in DNA. It bends and unwinds the DNA prior to transcription and the translation process.

 
Product Number Title Applications Host Clonality
AC16-0043 Anti-5-hydroxymethylcytosine (5-hmC) Antibody WB, IHC(F), IHC(P) Mouse Monoclonal (4D9)
AC16-0043-01 Anti-5-hydroxymethylcytosine (5-hmC) Antibody (AMCA) WB, IHC(F), IHC(P) Mouse Monoclonal (4D9)
AC16-0043-02 Anti-5-hydroxymethylcytosine (5-hmC) Antibody (AP) WB, IHC(F), IHC(P) Mouse Monoclonal (4D9)
AC16-0043-03 Anti-5-hydroxymethylcytosine (5-hmC) Antibody (APC) WB, IHC(F), IHC(P) Mouse Monoclonal (4D9)
AC16-0043-04 Anti-5-hydroxymethylcytosine (5-hmC) Antibody (APC-Cy5.5) WB, IHC(F), IHC(P) Mouse Monoclonal (4D9)
AC16-0043-05 Anti-5-hydroxymethylcytosine (5-hmC) Antibody (APC-Cy7) WB, IHC(F), IHC(P) Mouse Monoclonal (4D9)
AC16-0043-06 Anti-5-hydroxymethylcytosine (5-hmC) Antibody (Avidin) WB, IHC(F), IHC(P) Mouse Monoclonal (4D9)
AC16-0043-07 Anti-5-hydroxymethylcytosine (5-hmC) Antibody (Biotin) WB, IHC(F), IHC(P) Mouse Monoclonal (4D9)
AC16-0043-08 Anti-5-hydroxymethylcytosine (5-hmC) Antibody (BPE) WB, IHC(F), IHC(P) Mouse Monoclonal (4D9)
AC16-0043-09 Anti-5-hydroxymethylcytosine (5-hmC) Antibody (Cy3) WB, IHC(F), IHC(P) Mouse Monoclonal (4D9)
AC16-0043-10 Anti-5-hydroxymethylcytosine (5-hmC) Antibody (Cy5) WB, IHC(F), IHC(P) Mouse Monoclonal (4D9)
AC16-0043-11 Anti-5-hydroxymethylcytosine (5-hmC) Antibody (Cy5.5) WB, IHC(F), IHC(P) Mouse Monoclonal (4D9)