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T Cells

Immunology is the study of the immune system and its functions. The immune system can function in either specific, adaptive ways or in innate or non-specific ways. The adaptive immune system involves complex antigen-specific immune responses which are specialized and exclusive to certain invaders like bacteria, viruses, and other pathogens. Adaptive immunity is remembered, meaning responses against a re-visiting antigen are increasingly speedy and effective with each future attack. This is due to the rearrangement of DNA in each cell that occurs after an adaptive immune response so that future generations may inherent the ability to combat the specific pathogen. During an initial acquired immunity response, antigens are presented to lymphoid organs (lymph nodes, spleen, tonsils, bone marrow, thymus, etc.) so that B-lymphocytes (B cells) and T-lymphocytes (T cells) can be differentiated into effector cells and reproduced. Precursors to T cells are produced in the bone marrow and matured in the thymus (hence their name “T” cell). T cells have a T cell receptor on their surface. Different types of T cells exist. These include helper T cells, cytotoxic T cells, memory T cells, regulatory T cells, and natural killer T cells. Each type of T cell has a specific function in the adaptive immune response.

Anti-BAFF antibody binds against BAFF protein. BAFF is a cytokine belongs to the tumor necrosis factor family and is secreted and abundantly expressed on the cell membrane of blood leukocytes, monocytes, and macrophages. BAFF is expressed in lower concentrations in the spleen, lymph nodes, bone marrow, T-cells, dendritic cells, placenta, heart, lung, liver, thymus, and pancreas (lymphoid tissues). BAFF binds to receptors in order to stimulate B cell and T cell function. Anti-CD3 antibody has been used in research regarding B cell lymphoma as well as brain tumors. The CD3 complex is a mediator of signal transduction localized on the cell membrane. Defects in CD3 can cause several severe immunodeficiency disorders among a specific group of ailments characterized by low antibody levels and specific immunities due to poor T-cell development.

 
Product Number Title Applications Host Clonality
AC16-0033 Anti-CD4 Antibody ELISA, IHC(F), IHC(P), ICC, IF, IP, FC Rat Monoclonal (GK1.5)
AC16-0033-01 Anti-CD4 Antibody (AMCA) ELISA, IHC(F), IHC(P), ICC, IF, IP, FC Rat Monoclonal (GK1.5)
AC16-0033-02 Anti-CD4 Antibody (AP) ELISA, IHC(F), IHC(P), ICC, IF, IP, FC Rat Monoclonal (GK1.5)
AC16-0033-03 Anti-CD4 Antibody (APC) ELISA, IHC(F), IHC(P), ICC, IF, IP, FC Rat Monoclonal (GK1.5)
AC16-0033-04 Anti-CD4 Antibody (APC-Cy5.5) ELISA, IHC(F), IHC(P), ICC, IF, IP, FC Rat Monoclonal (GK1.5)
AC16-0033-05 Anti-CD4 Antibody (APC-Cy7) ELISA, IHC(F), IHC(P), ICC, IF, IP, FC Rat Monoclonal (GK1.5)
AC16-0033-06 Anti-CD4 Antibody (Avidin) ELISA, IHC(F), IHC(P), ICC, IF, IP, FC Rat Monoclonal (GK1.5)
AC16-0033-07 Anti-CD4 Antibody (Biotin) ELISA, IHC(F), IHC(P), ICC, IF, IP, FC Rat Monoclonal (GK1.5)
AC16-0033-08 Anti-CD4 Antibody (BPE) ELISA, IHC(F), IHC(P), ICC, IF, IP, FC Rat Monoclonal (GK1.5)
AC16-0033-09 Anti-CD4 Antibody (Cy3) ELISA, IHC(F), IHC(P), ICC, IF, IP, FC Rat Monoclonal (GK1.5)
AC16-0033-10 Anti-CD4 Antibody (Cy5) ELISA, IHC(F), IHC(P), ICC, IF, IP, FC Rat Monoclonal (GK1.5)
AC16-0033-11 Anti-CD4 Antibody (Cy5.5) ELISA, IHC(F), IHC(P), ICC, IF, IP, FC Rat Monoclonal (GK1.5)
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  1. ELISA (1327)
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  5. IF (600)
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  7. IHC (P) (1)
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  9. IHC(P) (69)
  10. IP (660)
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  12. WB (1304)
Conjugate
  1. Alexa FluorÔö¼┬½ 488 (5)
  2. Alexa FluorÔö¼┬½ 647 (6)
  3. Alexa FluorÔö¼┬½ 700 (10)
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  28. PerCP-Cy5.5 (77)
  29. PerCP-Cy™5.5 (8)
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  32. Streptavidin (77)
Clonality
  1. Monoclonal (14) (23)
  2. Monoclonal (145-2C11) (4)
  3. Monoclonal (17D9) (23)
  4. Monoclonal (1aG4/C5) (1)
  5. Monoclonal (1E7.2) (3)
  6. Monoclonal (341) (2)
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  14. Monoclonal (AC2) (23)
  15. Monoclonal (APA1/1) (3)
  16. Monoclonal (B72.3 + CC49) (23)
  17. Monoclonal (BA5b) (5)
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  33. Monoclonal (H146-968) (2)
  34. Monoclonal (H57-597) (1)
  35. Monoclonal (HB15e) (3)
  36. Monoclonal (HI149) (4)
  37. Monoclonal (HI30) (3)
  38. Monoclonal (IP26) (6)
  39. Monoclonal (IPO-38) (23)
  40. Monoclonal (IVA103) (1)
  41. Monoclonal (IVA94) (1)
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  72. Monoclonal (MEM-92) (2)
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  87. Monoclonal (SPM120) (23)
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  89. Monoclonal (SPM546) (23)
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  94. Monoclonal (SPM570) (23)
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  97. Monoclonal (UCH-L1) (23)
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  100. Monoclonal (UCHT1) (10)
  101. Monoclonal (UW60.1) (2)
  102. Monoclonal (V65) (3)
  103. Monoclonal (ZAP-03) (1)
  104. Polyclonal (1103)
Host Species
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