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RNA Polymerase

RNA polymerases are a group of enzymes whose main function is to identify and transcribe genes. It uses one strand of DNA as a template from which to produce the new strand of RNA. RNA has the ability to decipher genes on DNA and transcribe only those that are needed to be manufactured into proteins. It does this by recognizing a promotor region on the DNA strand itself. This promotor region is adjacent the DNA that encodes for the gene and serves as a flag. Once the promotor is identified, the gene can be prepared for translation. DNA itself exists as a double stranded molecule coiled around itself into a helix structure. In this state, it is inaccessible to translation. Another key role of RNA polymerase is to separate the DNA and make one single stranded area available to be used as a template. Then, the active site of the RNA polymerase enzyme can being to read the DNA bases, gather the complimentary RNA nucleotide, and transcribe a strand of RNA from the 3 prime end. Most organisms have many different types of RNA polymerase, each specializing in a certain aspect of transcription. For instance, in eukaryotes, RNA polymerase I transcribes most messenger RNAs, RNA polymerase II produces messenger RNAs and small RNAs, and RNA polymerase III transcribes rRNAs, 5srRNAs, and other smaller RNAs. Once the template strand has been identified, secluded, and copied by RNA polymerase, the RNA molecule is then ready to be transferred out of the nucleus so the protein can be manufactured. RNA polymerase is a very important part of DNA transcription. It not only does most of the physical transcription but also allows for the actual genetic material to remain safe inside the nucleus rather than being used directly for protein manufacture.

Anti-TBP like protein TLP antibody binds against the target TATA-binding protein like protein. TBP like protein TLP is localized in the cytoplasm and the nucleus of cells and is ubiquitously expressed in cells with the highest levels detected in the testis and the ovary. Although TATA-binding protein-like protein is involved in development, checkpoints, and apoptosis through the potentiation of gene expression, it does not actually have the ability to bind to TATA boxes or DNA. Anti-POLR2G antibody binds against the target RNA polymerase II subunit RPB7. POLR2G is the seventh largest subunit of RNA polymerase II. RNA polymerase II is responsible for synthesizing messenger RNA in eukaryotes.

 
Product Number Title Applications Host Clonality
AC21-2852 Anti-MED12 Antibody ELISA Goat Polyclonal
AC21-2958 Anti-BATF Antibody ELISA Goat Polyclonal
AC21-0250-01 Anti-TBP like Protein TLP Antibody (AMCA) ELISA, WB Goat Polyclonal
AC21-0250-02 Anti-TBP like Protein TLP Antibody (AP) ELISA, WB Goat Polyclonal
AC21-0250-03 Anti-TBP like Protein TLP Antibody (APC) ELISA, WB Goat Polyclonal
AC21-0250-04 Anti-TBP like Protein TLP Antibody (APC-Cy5.5) ELISA, WB Goat Polyclonal
AC21-0250-05 Anti-TBP like Protein TLP Antibody (APC-Cy7) ELISA, WB Goat Polyclonal
AC21-0250-06 Anti-TBP like Protein TLP Antibody (Avidin) ELISA, WB Goat Polyclonal
AC21-0250-07 Anti-TBP like Protein TLP Antibody (Biotin) ELISA, WB Goat Polyclonal
AC21-0250-08 Anti-TBP like Protein TLP Antibody (BPE) ELISA, WB Goat Polyclonal
AC21-0250-09 Anti-TBP like Protein TLP Antibody (Cy3) ELISA, WB Goat Polyclonal
AC21-0250-10 Anti-TBP like Protein TLP Antibody (Cy5) ELISA, WB Goat Polyclonal