Questions? Feedback? powered by Olark live chat software

PE-Cy™5 Antibodies

Conjugated antibodies are antibodies that have been joined or conjugated to a type of second molecule. The second molecule can be a toxin, radioisotope, or other label. Abcore-Inc. offers numerous conjugated antibodies that come labeled with a fluorescent dye and proteins. Conjugated antibodies are also called immonoconjugates and are mostly used in immunotherapy or in development of antibodies used to target specific tissues. There are a few, more newly developed, combination conjugates which include PerCP-Cy5.5, PE-Cy™5, PE-Dyomics 647, PE-Dyomics 590. PE-Cy™5 is a dual conjugate that can be attached to antibodies. Phycoerythrin, often abbreviated PE, is a fluorescent dye. PE is comparatively larger than many other types of conjugates and has a molecular weight of 240 kd. The molecule itself contains 25 fluors. Cyanin 5.1 dye, abbreviated Cy™5, is a member of the cyanine dye family. These dyes typically emit a shade of blue-green. Cy™5 has a maximum absorbance of 649 nm and maximum emission of 670 nm. PE-Cy™5 is also known as phyocoerythrin Cyanin 5.1, PC5, Cy-Chrome, and Tricolor. The maximum fluorescence emission of the combo is 670 nm. Due to the size of the molecule, there is typically only one PE-Cy5 molecule attached per antibody.

Anti-CD45 (PE-Cy™5) antibody (protein tyrosine phosphatase receptor type C antibody) binds against the target CD45 antigen. CD45 (leukocyte common antigen) is a protein tyrosine-protein phosphatase required to activate T-cells. CD45 is a positive regulator of T-cell coactivation that is localized in the membrane of cells. Once the T-cell has been activated by the CD45 activity, SKAP1 and FYN are recruited and dephosphorylated. Defects in protein tyrosine phosphatase receptor type C cause severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell positive and increase one’s susceptibility to multiple sclerosis. Severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell positive is a rare disease that presents with a fever, rash, hepatosplenomegal, lymphadenopathy, pneumonitis, and pancytopenia. It is a severe combined immunodeficiency. Multiple sclerosis is an inflammatory autoimmune disease characterized by plaques on the nerve fibers in the brain, spinal cord, and optic nerves. Anti-CD3 (PE-Cy™5) antibody has been used in research regarding B cell lymphoma as well as brain tumors. The CD3 complex is a mediator of signal transduction localized on the cell membrane. Defects in CD3 can cause several severe immunodeficiency disorders among a specific group of ailments characterized by low antibody levels and specific immunities due to poor T-cell development.

 
Product Number Title Applications Host Clonality
AC21-0175-15 Anti-Iba1 Antibody (PE-Cy5) ELISA, WB Goat Polyclonal
AC21-0683-15 Anti-Apolipoprotein E Antibody (PE-Cy5) ELISA, WB, IHC Goat Polyclonal
AC21-0778-15 Anti-Apolipoprotein J Antibody (PE-Cy5) ELISA, WB Goat Polyclonal
AC21-0889-15 Anti-Iba1 Antibody (PE-Cy5) ELISA, WB, IHC Goat Polyclonal
AC21-0929-15 Anti-Iba1 Antibody (PE-Cy5) ELISA, WB, IHC Goat Polyclonal
AC21-1072-15 Anti-Apolipoprotein M Antibody (PE-Cy5) ELISA, IHC Goat Polyclonal
AC21-1074-15 Anti-APOA4 Antibody (PE-Cy5) ELISA, WB, IHC Goat Polyclonal
AC21-1155-15 Anti-APOBEC3G Antibody (PE-Cy5) ELISA, WB Goat Polyclonal
AC21-1162-15 Anti-Apolipoprotein CI Antibody (PE-Cy5) ELISA, IHC Goat Polyclonal
AC21-1232-15 Anti-Apolipoprotein A V Antibody (PE-Cy5) ELISA, WB Goat Polyclonal
AC21-1413-15 Anti-PHO1 Antibody (PE-Cy5) ELISA, IHC Goat Polyclonal
AC21-1414-15 Anti-APOBEC4 Antibody (PE-Cy5) ELISA Goat Polyclonal
Refine By Clear All
Application
  1. ELISA (131)
  2. FC (110)
  3. FUNC (1)
  4. ICC (111)
  5. IF (110)
  6. IHC (120)
  7. IHC(F) (6)
  8. IHC(P) (5)
  9. IP (102)
  10. WB (158)
Conjugate
  1. PE-Cy5 (177)
  2. PE-Cy™5 (4)
  3. PE-Cy™5 (5)
Clonality
  1. Monoclonal (104D2) (1)
  2. Monoclonal (1SS-48) (1)
  3. Monoclonal (2-104) (1)
  4. Monoclonal (2-105) (1)
  5. Monoclonal (2-153) (1)
  6. Monoclonal (2C1) (1)
  7. Monoclonal (4G7 ) (1)
  8. Monoclonal (581) (1)
  9. Monoclonal (6-36) (1)
  10. Monoclonal (6-37) (1)
  11. Monoclonal (D5) (1)
  12. Monoclonal (DCS118) (1)
  13. Monoclonal (DCS211.6) (1)
  14. Monoclonal (HIT2) (1)
  15. Monoclonal (MEM-188) (1)
  16. Monoclonal (MEM-241) (1)
  17. Monoclonal (MEM-28) (1)
  18. Monoclonal (MOPC-21) (1)
  19. Monoclonal (ORP185) (1)
  20. Monoclonal (QBEND-10) (1)
  21. Monoclonal (SB46) (1)
  22. Monoclonal (SH54) (1)
  23. Monoclonal (SK15) (1)
  24. Monoclonal (SPM102) (1)
  25. Monoclonal (SPM115) (1)
  26. Monoclonal (SPM115+SPM116) (1)
  27. Monoclonal (SPM116) (1)
  28. Monoclonal (SPM122) (1)
  29. Monoclonal (SPM125) (1)
  30. Monoclonal (SPM128) (1)
  31. Monoclonal (SPM132) (1)
  32. Monoclonal (SPM134) (1)
  33. Monoclonal (SPM139) (1)
  34. Monoclonal (SPM142) (1)
  35. Monoclonal (SPM144) (1)
  36. Monoclonal (SPM148) (1)
  37. Monoclonal (SPM150) (1)
  38. Monoclonal (SPM160) (1)
  39. Monoclonal (SPM166) (1)
  40. Monoclonal (SPM192) (1)
  41. Monoclonal (SPM198) (1)
  42. Monoclonal (SPM213) (1)
  43. Monoclonal (SPM217) (1)
  44. Monoclonal (SPM221) (1)
  45. Monoclonal (SPM246) (1)
  46. Monoclonal (SPM248) (1)
  47. Monoclonal (SPM250) (1)
  48. Monoclonal (SPM252) (1)
  49. Monoclonal (SPM253) (1)
  50. Monoclonal (SPM259) (1)
  51. Monoclonal (SPM261) (1)
  52. Monoclonal (SPM263) (1)
  53. Monoclonal (SPM265) (1)
  54. Monoclonal (SPM266) (1)
  55. Monoclonal (SPM269) (1)
  56. Monoclonal (SPM275) (1)
  57. Monoclonal (SPM282) (1)
  58. Monoclonal (SPM286) (1)
  59. Monoclonal (SPM296) (1)
  60. Monoclonal (SPM297) (1)
  61. Monoclonal (SPM298) (1)
  62. Monoclonal (SPM310) (1)
  63. Monoclonal (SPM333) (1)
  64. Monoclonal (SPM342) (1)
  65. Monoclonal (SPM350) (1)
  66. Monoclonal (SPM354) (1)
  67. Monoclonal (SPM360) (1)
  68. Monoclonal (SPM375) (1)
  69. Monoclonal (SPM406) (1)
  70. Monoclonal (SPM427) (1)
  71. Monoclonal (SPM442) (1)
  72. Monoclonal (SPM453) (1)
  73. Monoclonal (SPM456) (1)
  74. Monoclonal (SPM469) (1)
  75. Monoclonal (SPM489) (1)
  76. Monoclonal (SPM503) (1)
  77. Monoclonal (SPM505) (1)
  78. Monoclonal (SPM507) (1)
  79. Monoclonal (SPM508) (1)
  80. Monoclonal (SPM510) (1)
  81. Monoclonal (SPM517) (1)
  82. Monoclonal (SPM520) (1)
  83. Monoclonal (SPM531) (1)
  84. Monoclonal (SPM532) (1)
  85. Monoclonal (SPM533) (1)
  86. Monoclonal (SPM536) (1)
  87. Monoclonal (SPM537) (1)
  88. Monoclonal (SPM538) (1)
  89. Monoclonal (SPM539) (1)
  90. Monoclonal (SPM540) (1)
  91. Monoclonal (SPM542) (1)
  92. Monoclonal (SPM543) (1)
  93. Monoclonal (SPM554) (1)
  94. Monoclonal (SPM555) (1)
  95. Monoclonal (SPM557) (1)
  96. Monoclonal (SPM558) (1)
  97. Monoclonal (SPM559) (1)
  98. Monoclonal (SPM560) (1)
  99. Monoclonal (SPM561) (1)
  100. Monoclonal (SPM562) (1)
  101. Monoclonal (SPM563) (1)
  102. Monoclonal (SPM564) (1)
  103. Monoclonal (SPM565) (1)
  104. Monoclonal (SPM566) (2)
  105. Monoclonal (SPM567) (1)
  106. Monoclonal (SPM568) (1)
  107. Monoclonal (SPM569) (1)
  108. Monoclonal (SPM569+SPM570) (1)
  109. Monoclonal (SPM570) (1)
  110. Monoclonal (SPM571) (1)
  111. Monoclonal (SPM572) (1)
  112. Monoclonal (SPM573) (1)
  113. Monoclonal (SPM574) (1)
  114. Monoclonal (SPM575) (1)
  115. Monoclonal (SPM576) (1)
  116. Monoclonal (SPM577) (1)
  117. Monoclonal (SPM578) (1)
  118. Monoclonal (SPM579) (1)
  119. Monoclonal (SPM580) (1)
  120. Monoclonal (SPM581) (1)
  121. Monoclonal (SPM582) (1)
  122. Monoclonal (SPM583) (1)
  123. Monoclonal (SPM588) (1)
  124. Monoclonal (SPM589) (1)
  125. Monoclonal (SPM590) (1)
  126. Monoclonal (SPM591) (1)
  127. Monoclonal (TC-113) (1)
  128. Monoclonal (TC-14) (1)
  129. Monoclonal (TC-19) (1)
  130. Monoclonal (UCHT1) (1)
  131. Polyclonal (55)
Host Species
  1. Goat (43)
  2. Mouse (130)
  3. Rabbit (12)
  4. Rat (1)