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Obesity Antibodies

Those suffering from obesity have an excess amount of body fat. A person has to be 20% or more above normal weight due to excess body fat in order to be considered obese. Morbid obesity is when a person is either 50% or 100% over the normal weight. Obesity occurs when a person consumes more calories than their body needs for energy on a daily basis. Obesity has a number of factors ranging from diet, lifestyle, age, gender, genetics, medication, illness, and psychological influences. Implications of obesity include prolonged emotional suffering and higher risk of many different health problems like heart disease, stroke, diabetes, and cancer. In the U.S.A., more than one third of adults and about one fifth of children are obese.

The 5HT3B receptor is one of several receptors for the neurochemical serotonin (5-hydroxytryptamine). Serotonin is a neurotransmitter and a hormone responsible for the regulation of satiety, hunger, mood, and sleep. Anti- 5HT3B antibody binds to this receptor in place of serotonin and can effectively block the binding of 5HT3B. The receptor itself is cation exclusive but otherwise is a comparatively non-selective ion channel. Defects in serotonin receptors can lead to disorders like depression, obesity, autism, and problems with sleep. The anti-CPT1A antibody binds against CPT1A antigen. Carnitine palmitoyltransferase 1 belongs to the carnitine/choline acetyltransferase family and is localized on the outer membrane of the mitochondria. CPT1A is highly expressed in the kidney and heart and expressed somewhat in the liver and skeletal muscles. CPT1A is involved in lipid metabolism and fatty acid beta-oxidation. Defects in carnitine palmitoyltransferase liver antibody or the target protein are the cause of carnitine palmitoyltransferase 1A deficiency. Carnitine palmitoyltransferase 1A deficiency is a disorder of long-chain fatty acid oxidation. Individuals with carnitine palmitoyltransferase 1A deficiency have gastrointestinal symptoms like hypoglycemia with high energy demands, illness, or after fasting.

 
Product Number Title Applications Host Clonality
AC16-0049 Anti-FTO Antibody WB, IHC(F), ICC, IF, FC Rabbit Polyclonal
AC21-2691 Anti-Estrogen Receptor Beta Antibody ELISA, WB Goat Polyclonal
AC21-2741 Anti-5HT2A Receptor Antibody ELISA Goat Polyclonal
AC21-2747 Anti-IL15 Antibody ELISA, WB Goat Polyclonal
AC21-2804 Anti-SIRT1 Antibody ELISA, WB Goat Polyclonal
AC21-2971 Anti-MC4 Receptor Antibody ELISA, WB Goat Polyclonal
AC21-0048-01 Anti-SH2B1 Antibody (AMCA) ELISA Goat Polyclonal
AC21-0048-02 Anti-SH2B1 Antibody (AP) ELISA Goat Polyclonal
AC21-0048-03 Anti-SH2B1 Antibody (APC) ELISA Goat Polyclonal
AC21-0048-04 Anti-SH2B1 Antibody (APC-Cy5.5) ELISA Goat Polyclonal
AC21-0048-05 Anti-SH2B1 Antibody (APC-Cy7) ELISA Goat Polyclonal
AC21-0048-06 Anti-SH2B1 Antibody (Avidin) ELISA Goat Polyclonal