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Neuronal Markers

Neurons are specialized cells of the nervous system designed to transmit chemical and electrical signals throughout the body. A biological marker is an indicator of a biological state. Often times it may be difficult to take biopsy or living tissue sample for medical diagnostics or scientific research purposes. Neuronal markers make it easier to look into the nervous system. Neuronal markers are present in the brain and peripheral nervous system and are indicative of certain neuronal diseases, statuses, or conditions. Neuronal markers are typically very effective diagnostic or prognostic tools in the treatment of sickness. These biomarkers can also be used to identify neural cells or detect expression details of certain types of molecules. Neuron markers sold by Abcore Inc. can be categorized into axon markers, dendrite markers, growth cone markers, soma markers, and synapse markers.

Anti-choline acetyltransferase antibody binds against choline acetyltransferase. Choline acetyltransferase catalyzes the synthesis of acetylcholine from acetyl CoA and choline at the cholinergic synapses. Defects in CHAT are the cause of congenital myasthenic syndrome with episodic apnea. Congenital myasthenic syndrome with episodic apnea is a rare form of apnea that is present in infants. The disease is characterized by muscular weakness, secondary respiratory infections, poor infant sucking, fluctuating ptosis (eyelid droopiness), and fatigue. Anti-myelin protein zero antibody binds against the target myelin protein zero. Myelin protein zero is localized on membranes and found only in the peripheral nervous system Schwann cells. The protein is implicated in creating the extracellular membrane face which can guide the wrapping process of adjacent lamellae. Defects in myelin protein zero are the cause of Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, hypomyelination neuropathy, and Roussy-Levy syndrome. Charcot-Marie-Tooth disease is a group of genetic disorders that affects peripheral nerves. People affected with Charcot-Marie-Tooth disease experience a loss of touch sensation in the peripheral limbs and neuropathic pain. Dejerine-Sottas syndrome is a hereditary motor disease characterized by moderate to severe lower and upper extremity weakness. Onset occurs in infancy and early childhood with typically slow progression until the teenage years where the disease than progresses rapidly. Hypomyelination neuropathy is a neurological disorder present at birth characterized by respiratory difficulty, muscle weakness, and loss of coordination. Roussy-Levy syndrome is a neuromuscular disorder characterized by poor judgment of movement, absence of reflexes, and muscle atrophy.

 
Product Number Title Applications Host Clonality
AC21-1347-01 Anti-14-3-3 Tau Antibody (AMCA) ELISA, WB Goat Polyclonal
AC16-0064 Anti-Synaptopodin Antibody WB, IHC(F), IHC(P) Mouse Monoclonal (G1D4)
AC16-0072 Anti-BrdU Antibody WB, IHC(F), IHC(P), ICC, IF, FC Rat Monoclonal (BU1/75)
AC16-0064-01 Anti-Synaptopodin Antibody (AMCA) WB, IHC(F), IHC(P) Mouse Monoclonal (G1D4)
AC16-0064-02 Anti-Synaptopodin Antibody (AP) WB, IHC(F), IHC(P) Mouse Monoclonal (G1D4)
AC16-0064-03 Anti-Synaptopodin Antibody (APC) WB, IHC(F), IHC(P) Mouse Monoclonal (G1D4)
AC16-0064-04 Anti-Synaptopodin Antibody (APC-Cy5.5) WB, IHC(F), IHC(P) Mouse Monoclonal (G1D4)
AC16-0064-05 Anti-Synaptopodin Antibody (APC-Cy7) WB, IHC(F), IHC(P) Mouse Monoclonal (G1D4)
AC16-0064-06 Anti-Synaptopodin Antibody (Avidin) WB, IHC(F), IHC(P) Mouse Monoclonal (G1D4)
AC21-2700 Anti-Synaptotagmin VI Antibody ELISA Goat Polyclonal
AC21-2703 Anti-Synaptotagmin V Antibody ELISA, WB Goat Polyclonal
AC21-2708 Anti-Doublecortin Antibody ELISA, WB Goat Polyclonal
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  1. Axon Markers (213)
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  5. Synapse Markers (867)
Application
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Conjugate
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Clonality
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