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Microfilaments

Microfilaments, also known as actin filaments, are small filaments that form an important component of the cytoskeleton. Microfilaments have the structure of a tiny rod that ranges from 5 to 9 nanometers in diameter. Despite their small size, they are designed to bear large amounts of tension and are relatively strong. Microfilaments are polar structures made of globular actin (G-actin) monomer subunits joined together to form filamentous actin (F-actin) or a polymerized actin microfilament. The function of microfilaments is to maintain the structure of the cell and aid in cell movement and cellular contraction.

The anti-actin antibody will react with all 6 known vertebrate isoforms of actin. This antibody is useful in cancer research or more specifically the apoptosis or death of receptors and ligands. It is also useful in research surrounding signal transduction between actins using crosslinking. Defects in the actin cause myopathy or severe muscular weakness. Anti-syntrophin alpha 1 antibody binds against the target syntrophin alpha 1. Syntrophin alpha 1 is localized in the cell membrane, cell junction, and cytoplasm. It is highly expressed in skeletal muscle and heart. Syntrophin alpha 1 is an adapter protein that binds to and organizes subcellular localization of a variety of membrane proteins. Defects in SNTA1 are the cause of long QT syndrome type 12. Long QT syndrome is a type of rare heart condition causing an irregular ventricular heartbeat (TDP) which can lead to fainting and sudden death.

 
Product Number Title Applications Host Clonality
AC21-2644 Anti-ARPC1A Antibody ELISA, WB Goat Polyclonal
AC21-2753 Anti-ENC1 Antibody ELISA, WB Goat Polyclonal
AC21-2758 Anti-Cardiac Troponin T Antibody ELISA, WB Goat Polyclonal
AC21-2776 Anti-PDLIM2 Antibody ELISA, WB Goat Polyclonal
AC21-2783 Anti-Myotilin Antibody ELISA, WB Goat Polyclonal
AC21-2793 Anti-Troponin T1 Antibody ELISA Goat Polyclonal
AC21-2810 Anti-Fascin Antibody ELISA, WB Goat Polyclonal
AC21-2823 Anti-WAVE 1 Antibody ELISA Goat Polyclonal
AC21-2872 Anti-Gelsolin Antibody ELISA, WB Goat Polyclonal
AC21-2944 Anti-TNNT3 Antibody ELISA, WB Goat Polyclonal
AC21-2945 Anti-Troponin I fast skeletal muscle Antibody ELISA, WB Goat Polyclonal
AC21-2946 Anti-Troponin I fast skeletal muscle Antibody ELISA, WB Goat Polyclonal