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Intracellular Molecules

Intracellular molecules are involved in the communication or signal transduction within a cell. Intracellular receptors like nuclear and cytoplasmic receptors are proteins that are localized within their specific areas. Some intracellular molecules can directly enter a cell. These include hydrophobic molecules like steroid hormones and nitric oxide. Other signals within a cell are used to communicate messages inside of the cell by way of receptors across membranes like G-protein coupled receptors, ion-liked receptors, and enzyme linked receptors. These receptors are located on internal membranes rather than on the external cell membrane. The ligands that bind to them are usually intracellular second messengers or intracrine peptide hormones.

Anti-SOCS3 antibody binds against the target SOCS3. SOCS3 is expressed in the heart, placenta, skeletal muscle, peripheral blood leukocytes, lung, and kidney. It is a negative regulator of cytokines. Defects in SOCS3 are implicated in atopic dermatitis. Atopic dermatitis is a chronic skin disorder that involves scaly and itchy rashes. Symptoms include blisters, discharge, raw skin, redness, and inflammation. Anti-GATA1 antibody binds against the target GATA1. GATA 1 is localized in the nucleus and expressed in erythrocytes. The protein is a transcriptional activator which serves in erythroid development. Defects in GATA1 are the cause of X-linked dyserythropoietic anemia with or without thrombocytopenia. Dyserythropoietic anemia is a condition that affects blood cells and occurs primarily in males (who have only one copy of the affected X chromosome). The red blood cells are improperly formed and do not function into mature blood cells.

 
Product Number Title Applications Host Clonality
AC21-2775 Anti-CD97 Antibody ELISA, WB Goat Polyclonal
AC21-0018-01 Anti-SOCS3 Antibody (AMCA) ELISA, WB Goat Polyclonal
AC21-0018-02 Anti-SOCS3 Antibody (AP) ELISA, WB Goat Polyclonal
AC21-0018-03 Anti-SOCS3 Antibody (APC) ELISA, WB Goat Polyclonal
AC21-0018-04 Anti-SOCS3 Antibody (APC-Cy5.5) ELISA, WB Goat Polyclonal
AC21-0018-05 Anti-SOCS3 Antibody (APC-Cy7) ELISA, WB Goat Polyclonal
AC21-0018-06 Anti-SOCS3 Antibody (Avidin) ELISA, WB Goat Polyclonal
AC21-0018-07 Anti-SOCS3 Antibody (Biotin) ELISA, WB Goat Polyclonal
AC21-0018-08 Anti-SOCS3 Antibody (BPE) ELISA, WB Goat Polyclonal
AC21-0018-09 Anti-SOCS3 Antibody (Cy3) ELISA, WB Goat Polyclonal
AC21-0018-10 Anti-SOCS3 Antibody (Cy5) ELISA, WB Goat Polyclonal
AC21-0018-11 Anti-SOCS3 Antibody (Cy5.5) ELISA, WB Goat Polyclonal