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Insulin Related

Insulin is a hormone produced by the islets of Langerhans in the pancreas and released in response to increasing levels of sugar in the blood stream. Insulin is a peptide hormone consisting of 51 amino acids and has a molecular weight of 5808 Da. Although its main function is carbohydrate metabolism, insulin serves a myriad of important roles. The liver cells, muscle cells, and fat cells respond to increasing insulin by taking glucose from the blood and converting it to glycogen. The presence of insulin in circulation also prevents the use of fat, or ketones, as a fuel for bodily metabolism. Insulin also controls and regulates amino acid (protein) degradation and uptake by body cells. When there is insufficient insulin due to lack of production or insulin resistance, disorders like diabetes mellitus can occur.

Anti-IGF1 antibody binds against the target insulin like growth factor 1. Insulin like growth factor 1 is secreted by cells and belongs to the insulin family. This insulin related molecule is isolated from plasma and is structurally and functionally similar to insulin but has a much higher growth-promoting activity. Defects in IGF1 are the cause of insulin-like growth factor 1 deficiency. Insulin-like growth factor 1 deficiency is a relatively newly discovered disorder. Affected children will show short stature and retarted growth. Treatment includes hormone therapy. Anti-chromogranin A antibody binds against the target chromogranin A. Chromogranin A is secreted by neuroendocrine and endocrine secretory granules. It is a pancreastatin that inhibits glucose induced insulin release from the pancreas.

 
Product Number Title Applications Host Clonality
AC16-0041 Anti-Visfatin Antibody ELISA, WB, IHC(F), IHC(P) Rat Monoclonal (14A5)
AC16-0041-01 Anti-Visfatin Antibody (AMCA) ELISA, WB, IHC(F), IHC(P) Rat Monoclonal (14A5)
AC16-0041-02 Anti-Visfatin Antibody (AP) ELISA, WB, IHC(F), IHC(P) Rat Monoclonal (14A5)
AC16-0041-03 Anti-Visfatin Antibody (APC) ELISA, WB, IHC(F), IHC(P) Rat Monoclonal (14A5)
AC16-0041-04 Anti-Visfatin Antibody (APC-Cy5.5) ELISA, WB, IHC(F), IHC(P) Rat Monoclonal (14A5)
AC16-0041-05 Anti-Visfatin Antibody (APC-Cy7) ELISA, WB, IHC(F), IHC(P) Rat Monoclonal (14A5)
AC16-0041-06 Anti-Visfatin Antibody (Avidin) ELISA, WB, IHC(F), IHC(P) Rat Monoclonal (14A5)
AC16-0041-07 Anti-Visfatin Antibody (Biotin) ELISA, WB, IHC(F), IHC(P) Rat Monoclonal (14A5)
AC16-0041-08 Anti-Visfatin Antibody (BPE) ELISA, WB, IHC(F), IHC(P) Rat Monoclonal (14A5)
AC16-0041-09 Anti-Visfatin Antibody (Cy3) ELISA, WB, IHC(F), IHC(P) Rat Monoclonal (14A5)
AC16-0041-10 Anti-Visfatin Antibody (Cy5) ELISA, WB, IHC(F), IHC(P) Rat Monoclonal (14A5)
AC16-0041-11 Anti-Visfatin Antibody (Cy5.5) ELISA, WB, IHC(F), IHC(P) Rat Monoclonal (14A5)