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Energy Metabolism

The body's energy metabolism is a conglomeration of all of the bodily processes. These processes are how the body uses, stores, and burns energy. The set of chemical reactions that make up energy metabolism allow the organism to grow, maintain their structures, and react to their environments. There are two main categories of metabolic routes labeled either catabolic (catabolism- destructive metabolism) or anabolic (anabolism- constructive metabolism). Simplified, anabolic pathways use chemical energy to power cellular work while catabolic pathways break down larger molecules and release their energy in that way. Furthermore, anabolism builds large complex molecules and consumes the energy produced by catabolism. The complex molecules produced by anabolism are polymers composed of many monomers. In proteins for example, the monomer would be the amino acid and the polymer would be the protein. Hormones used by anabolic processes stimulate or otherwise control anabolism and include growth hormone, insulin-like growth factors, insulin, testosterone, and estrogen. Most of these anabolic processes are powered by adenosine triphosphate (ATP). Catabolism is the breakdown of complex molecules into simpler ones that release energy in the process. The larger molecular polysaccharides (carbohydrates), lipids (fats), nucleic acids, and proteins are broken down into monosaccharides, fatty acids, nucleotides, and amino acids. Sometimes, the monomers can be further broken down into their components which often produce waste products like lactic acid, acetic acid (vinegar), carbon dioxide, ammonia, and urea. This catabolism produces ATP which can be used to fuel other anabolic processes like glycolysis, the citric acid cycle, muscle metabolism (breaking down muscles into amino acids), and fat metabolism. Hormones that stimulate or otherwise control catabolism include cortisol, glucagon, and adrenaline.

Anti-ABCA12 antibody binds against ATP binding cassette sub family A member 12. ABCA12 is a transporter involved in lipid homeostasis. ATB binding cassette sub gamily A member 12 is localized on the cell membrane and mainly expressed in the stomach, placenta, testis, and fetal brain. Defects in ABCA12 are the cause of ichthyosis harlequin (harlequin fetus) and ichthyosis lamellara type 2. Harlequin baby (fetus) is a skin disease characterized by a thick keratin layer of skin on the fetus or newborn baby. Symptoms include severe cranial and facial deformities, and the nose and ears are either underdeveloped or completely absent. In those with ichthyosis harlequin, their skin grows extremely rapidly and has to be rubbed off. The disease is often fatal although newer treatments are increasing life expectancy of those suffering from the disorder. Lamellar ichthyosis is a skin disorder which presents at birth with the baby seemingly covered in a shiny waxy membrane. Shortly after birth, this membrane is shed, and the skin begins to scale. At times, the baby's skin will revert to normal on its own, while others will progress into a more complicated skin disorder. Anti-5 lipoxygenase antibody binds against 5 lipoxygenase. 5 lipoxygenase catalyzes the first step in leukotriene biosynthesis and thus plays a role in inflammatory processes. 5 lipoxygenase is localized in the cytoplasm, and nuclear membrane.

 
Product Number Title Applications Host Clonality
AC15-0119 Anti-Creatine Kinase MM Antibody ELISA, WB, IHC, ICC, IF Goat Polyclonal
AC16-0010 Anti-GAPDH Antibody WB, IHC(F), IHC(P), ICC, IF, IP, FC Mouse Monoclonal (6C5)
AC16-0010-01 Anti-GAPDH Antibody (AMCA) WB, IHC(F), IHC(P), ICC, IF, IP, FC Mouse Monoclonal (6C5)
AC16-0010-02 Anti-GAPDH Antibody (AP) WB, IHC(F), IHC(P), ICC, IF, IP, FC Mouse Monoclonal (6C5)
AC16-0010-03 Anti-GAPDH Antibody (APC) WB, IHC(F), IHC(P), ICC, IF, IP, FC Mouse Monoclonal (6C5)
AC16-0010-04 Anti-GAPDH Antibody (APC-Cy5.5) WB, IHC(F), IHC(P), ICC, IF, IP, FC Mouse Monoclonal (6C5)
AC16-0010-05 Anti-GAPDH Antibody (APC-Cy7) WB, IHC(F), IHC(P), ICC, IF, IP, FC Mouse Monoclonal (6C5)
AC16-0010-06 Anti-GAPDH Antibody (Avidin) WB, IHC(F), IHC(P), ICC, IF, IP, FC Mouse Monoclonal (6C5)
AC16-0010-07 Anti-GAPDH Antibody (Biotin) WB, IHC(F), IHC(P), ICC, IF, IP, FC Mouse Monoclonal (6C5)
AC16-0010-08 Anti-GAPDH Antibody (BPE) WB, IHC(F), IHC(P), ICC, IF, IP, FC Mouse Monoclonal (6C5)
AC16-0010-09 Anti-GAPDH Antibody (Cy3) WB, IHC(F), IHC(P), ICC, IF, IP, FC Mouse Monoclonal (6C5)
AC16-0010-10 Anti-GAPDH Antibody (Cy5) WB, IHC(F), IHC(P), ICC, IF, IP, FC Mouse Monoclonal (6C5)