Questions? Feedback? powered by Olark live chat software

Endoderm Markers

The endoderm is one of the three germ layers of a developing animal embryo. The endoderm is the inner layer of the three layers in triploblastic animals. The endoderm contains cells that later develop into the epithelial lining of the digestive tract, associated glands, and the respiratory system. These structures include the stomach, colon, intestines, mouth, rectum, endocrine glands (liver, pancreas, and gall bladder), trachea, bronchi, and alveoli of the lungs. Different types of cells exist in the endoderm which can later develop into different types of cells in either the respiratory or digestive tract. These include primitive, visceral, and parietal endodermic cells. Each type of cell contains markers, and all types of endodermal cells can also share many molecular markers. Endodermal lineage markers are used to study the endodermal cells and determine which cells go where when forming the organs and tissues.

Anti-intestinal FABP antibody binds against the fatty acid binding proteins. Fatty acid binding proteins play a role in intracellular transport of fatty acids. FABP is expressed in the cytoplasm of cells in the small intestine and large intestine, especially the jejunum. Fatty acid binding proteins may play a role in metabolic diseases such as metabolic syndromes and atherosclerosis. Metabolic syndromes include coronary artery disease, stroke, and type 2 diabetes. Atherosclerosis is the hardening of the arteries caused by plaque buildup inside the arteries which can lead to heart attacks, strokes, and peripheral vascular disease. Anti-FGF 23 antibody binds against the target fibroblast growth factor 23. Fibroblast growth factor 23 is secreted by cells and expressed in osteogenic cells which are active during bone remodeling. FGF 23 is a regulator of phosphate homeostasis. Defects in FGF23 are the cause of autosomal dominant hypophosphatemic rickets and hyperphosphatemic familial tumoral calcinosis. Rickets is a disorder caused by a lack of vitamin D, calcium, or phosphate. These deficiencies lead to soft and weak bones. Hypophosphatemic Rickets is a form of rickets characterized by low phosphate levels and resistence to normal treatments like radiation and vitamin D supplementation. Tumoral calcinosis is a disorder characterized by calcium deposits in the soft tissue area around joints.

 
Product Number Title Applications Host Clonality
AC21-2805 Anti-Stra6 Antibody ELISA, WB Goat Polyclonal
AC21-2885 Anti-Stra6 Antibody ELISA Goat Polyclonal
AC21-0388-01 Anti-FOXA2 Antibody (AMCA) ELISA, WB Goat Polyclonal
AC21-0388-02 Anti-FOXA2 Antibody (AP) ELISA, WB Goat Polyclonal
AC21-0388-03 Anti-FOXA2 Antibody (APC) ELISA, WB Goat Polyclonal
AC21-0388-04 Anti-FOXA2 Antibody (APC-Cy5.5) ELISA, WB Goat Polyclonal
AC21-0388-05 Anti-FOXA2 Antibody (APC-Cy7) ELISA, WB Goat Polyclonal
AC21-0388-06 Anti-FOXA2 Antibody (Avidin) ELISA, WB Goat Polyclonal
AC21-0388-07 Anti-FOXA2 Antibody (Biotin) ELISA, WB Goat Polyclonal
AC21-0388-08 Anti-FOXA2 Antibody (BPE) ELISA, WB Goat Polyclonal
AC21-0388-09 Anti-FOXA2 Antibody (Cy3) ELISA, WB Goat Polyclonal
AC21-0388-10 Anti-FOXA2 Antibody (Cy5) ELISA, WB Goat Polyclonal