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Dyomics Antibodies

Dyomics offers many different fluorescent labels and conjugates for bioanalytical and diagnostic applications. Dyomics focuses on the red and NIR region of the fluorescents. Dyomics is a company that provides these dyes for bioanalysis and related fields of high technology. Abcore Inc. offers many antibodies already conjugated to the labels offered by Dyomics. Dyomics 547, or DY-547, absorbs and emits light at 557 nm and 574 nm in Ethanol. Dyomics 547 belongs to the green excitation group. Dyomics 547 is made of trimethine cyanine and is soluble in water, methanol, DMF, and DMSO. Dyomics 547 antibodies are useful for protein labeling, microarray experiments, FisH microscopy, and gel electrophoresis. It is compatible with Alexa Fluor® 535. Dy-547 is sometimes used in conjunction with Dy-647. Dyomics 647 absorbs and emits light at 653 nm and 672 nm respectively (in Ethanol). Dy-647 is a pentamethine based bluorophore that is soluble in water, methanol, DMF, and DMSO. It produces a red excitation. It is similar with Alexa Fluor® 647. Dyomics 647 antibodies are useful for protein labeling, microarray experiments, FisH microscopy, and gel electrophoresis.

Anti-Vimentin antibody (Dyomics 547) bings against vimentin. Vimentins belong to the intermediate filament family and are class III intermediate filaments. Vimentin is found in the cytoplasm of cells and is highly expressed in fibroblasts, lymphocytes, and some mammary carcinoma cell lines. Vimentin attaches to the nucleus, the endoplasmic reticulum and the mitochondria in the cell. Deficiencies in vimentin are common in those suffereing from Burkitt’s lymphoma. Burkitt’s lymphoma is a rare form of lymphoma typically affecting kids and young adults. If left untreated it will overtake the body in as little as a few days. Common treatments of Burkitt’s lymphoma include highly aggressive chemotherapy for a long period of time using agents like vincristine (Oncovin), Adriamycin, Cytoxan and steroid treatment with prednisone. Treatment is successful in getting about half of affected individuals into a lasting remission. Symptoms of Burkitt’s include swollen lymph nodes. Tests like biopsy of the bone marrow and lymph nodes and complete blood counts can be useful in diagnosing Burkitt’s lymphoma. Anti-CD2 antibody (Dyomics 647) binds against CD2. CD2 is expressed in the membrane of cells and interacts with lymphocyte functions by mediating adhesion between T-cells and other types of cells. CD2 is a cell adhesion molecule found on the surface of T-cells and natural killer (NK) cells. CD2 is a specific marker for the T-cells and NK cells, and thus is very useful in bioanalytic techniques like immunohistochemistry to detect the presence of T-cells and NK cells in tissue sections.

 
Product Number Title Applications Host Clonality
1C-250 Anti-alpha Tubulin Antibody (Dyomics 547) WB, IHC(P), ICC Mouse Monoclonal (TU-01)
1C-254 Anti-Vimentin Antibody (Dyomics 547) WB, ICC Mouse Monoclonal (VI-01)
1D-465 Anti-gamma Tubulin Antibody (Dyomics 647) WB, ICC Mouse Monoclonal (TU-30)
1D-496 Anti-Ku80 Antibody (Dyomics 647) ICC, IP Mouse Monoclonal (MEM-54)