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Dyomics 547 Antibodies

Dyomics 547, or DY-547, absorbs and emits light at 557 nm and 574 nm in Ethanol. Dyomics 547 belongs to the green excitation group. Dyomics 547 is made of trimethine cyanine and is soluble in water, methanol, DMF, and DMSO. Dyomics 547 antibodies are useful for protein labeling, microarray experiments, FisH microscopy, and gel electrophoresis. It is compatible with Alexa Fluor® 535. Dy-547 is sometimes used in conjunction with Dy-647.

Anti-Vimentin antibody (Dyomics 547) bings against vimentin. Vimentins belong to the intermediate filament family and are class III intermediate filaments. Vimentin is found in the cytoplasm of cells and is highly expressed in fibroblasts, lymphocytes, and some mammary carcinoma cell lines. Vimentin attaches to the nucleus, the endoplasmic reticulum, and the mitochondria in the cell. Deficiencies in vimentin are common in those suffering from Burkitt’s lymphoma. Burkitt’s lymphoma is a rare form of lymphoma typically affecting kids and young adults. If left untreated it will overtake the body in as little as a few days. Common treatments of Burkitt’s lymphoma include highly aggressive chemotherapy for a long period of time using agents like vincristine (Oncovin), Adriamycin, Cytoxan and steroid treatment with prednisone. Treatment is successful in getting about half of affected individuals into a lasting remission. Symptoms of Burkitt’s include swollen lymph nodes. Tests like biopsy of the bone marrow and lymph nodes and complete blood counts can be useful in diagnosing Burkitt’s lymphoma.

 
Product Number Title Applications Host Clonality
1C-250 Anti-alpha Tubulin Antibody (Dyomics 547) WB, IHC(P), ICC Mouse Monoclonal (TU-01)
1C-254 Anti-Vimentin Antibody (Dyomics 547) WB, ICC Mouse Monoclonal (VI-01)