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Cytoskeleton

The cytoskeleton of a cell includes actin filaments, microtubules, intermediate filaments, centrosomes, nuclear lamina, and the cell nucleus. These proteins form the scaffolding of a cell and effectively give it structure to hold the cell contents inside. There are numerous structures on the outer surface of the cytoskeleton. These structures include flagella, cilia, and lemellipodia. These outer surface molecules play elementary roles in cell mobility and division. The majority of these microfilaments are actin filaments which shrink and enlarge in order to power the cell as it moves around. Cytoskeleton antibodies will bind to antigens on cytoskeleton proteins.

The anti-actin antibody will react with all 6 known vertebrate isoforms of actin. This antibody is useful in cancer research or more specifically the apoptosis or death of receptors and ligands. It is also useful in research surrounding signal transduction between actins using crosslinking. Defects in the actin cause myopathy or severe muscular weakness. The anti- neuroserpin antibody has roles in serine protease inhibitors. It may be involved in the protein that reorganizes synaptic connections and protects neurons from cell damage. Defects in neuroserpin cause genetic encephalopathy characterized by inherited dementia.

 
Product Number Title Applications Host Clonality
AC16-0063 Anti-Smoothelin Antibody WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-01 Anti-Smoothelin Antibody (AMCA) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-02 Anti-Smoothelin Antibody (AP) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-03 Anti-Smoothelin Antibody (APC) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-04 Anti-Smoothelin Antibody (APC-Cy5.5) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-05 Anti-Smoothelin Antibody (APC-Cy7) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-06 Anti-Smoothelin Antibody (Avidin) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-07 Anti-Smoothelin Antibody (Biotin) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-08 Anti-Smoothelin Antibody (BPE) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-09 Anti-Smoothelin Antibody (Cy3) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-10 Anti-Smoothelin Antibody (Cy5) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-11 Anti-Smoothelin Antibody (Cy5.5) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
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Category
  1. Intermediate Filaments (1510)
  2. Microfilaments (2123)
  3. Microtubules (486)
  4. Motor Proteins (605)
Application
  1. EIA (46)
  2. ELISA (4188)
  3. FC (1330)
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  7. IHC(F) (5)
  8. IHC(P) (41)
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Conjugate
  1. Alexa FluorÔö¼┬½ 488 (4)
  2. Alexa FluorÔö¼┬½ 700 (1)
  3. AMCA (198)
  4. AP (198)
  5. APC (199)
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  27. Streptavidin (198)
Clonality
  1. Monoclonal (100/D5) (23)
  2. Monoclonal (124) (23)
  3. Monoclonal (158-4D3) (23)
  4. Monoclonal (1A4; same as asm-1) (23)
  5. Monoclonal (2B11) (23)
  6. Monoclonal (2D2) (23)
  7. Monoclonal (2F6) (23)
  8. Monoclonal (2H11+6E1) (23)
  9. Monoclonal (2H12) (23)
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  11. Monoclonal (3F7B5) (23)
  12. Monoclonal (57) (23)
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  14. Monoclonal (8C8) (23)
  15. Monoclonal (A53-B/A2) (3)
  16. Monoclonal (A53-B/A2.26; same as Ks19.1) (23)
  17. Monoclonal (AH26 + 57) (23)
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  19. Monoclonal (B1D8) (23)
  20. Monoclonal (B6.2) (23)
  21. Monoclonal (BA-17) (2)
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  24. Monoclonal (C-04) (5)
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  30. Monoclonal (C31.3 + JC/70A) (23)
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  33. Monoclonal (DC-10) (3)
  34. Monoclonal (DCS-6) (23)
  35. Monoclonal (DE-K13) (1)
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  40. Monoclonal (EM-22) (1)
  41. Monoclonal (ER505) (23)
  42. Monoclonal (ER506) (23)
  43. Monoclonal (GA-5) (1)
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  48. Monoclonal (J2D10) (23)
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  50. Monoclonal (KLC264) (23)
  51. Monoclonal (KN-01) (1)
  52. Monoclonal (KN-02) (1)
  53. Monoclonal (KN-03) (1)
  54. Monoclonal (LH2) (23)
  55. Monoclonal (LK1) (23)
  56. Monoclonal (LP1K) (23)
  57. Monoclonal (NF-01) (1)
  58. Monoclonal (NF-05) (1)
  59. Monoclonal (NF-09) (1)
  60. Monoclonal (PD7/26) (23)
  61. Monoclonal (PRLR742) (23)
  62. Monoclonal (R4A) (23)
  63. Monoclonal (SPM115) (23)
  64. Monoclonal (SPM115+SPM116) (23)
  65. Monoclonal (SPM116) (23)
  66. Monoclonal (SPM160) (23)
  67. Monoclonal (SPM192) (23)
  68. Monoclonal (SPM248) (23)
  69. Monoclonal (SPM261) (23)
  70. Monoclonal (SPM263) (23)
  71. Monoclonal (SPM265) (23)
  72. Monoclonal (SPM266) (23)
  73. Monoclonal (SPM269) (23)
  74. Monoclonal (SPM332) (23)
  75. Monoclonal (SPM507) (23)
  76. Monoclonal (SPM510) (23)
  77. Monoclonal (SPM538) (23)
  78. Monoclonal (SPM560) (23)
  79. Monoclonal (SPM561) (23)
  80. Monoclonal (SPM562) (23)
  81. Monoclonal (SPM563) (23)
  82. Monoclonal (SPM576) (23)
  83. Monoclonal (SPM583) (23)
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  98. Monoclonal (UCHL-1) (23)
  99. Monoclonal (VI-01) (2)
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  102. Monoclonal (VIK-10) (1)
  103. Polyclonal (3138)
Host Species
  1. Goat (3090)
  2. Mouse (1487)
  3. Rabbit (48)