Questions? Feedback? powered by Olark live chat software

Complement System

The complement system assists an antibody or phagocytic cell to clear pathogens from an organism. The complement system contains many small proteins that are activated by a wide array of triggers. Upon activation, proteases cleave the proteins to release cytokines and initiate a cascade that results in the eventual amplification and activation of a membrane attack complex. The complement system can be activated by the innate immune response to invading molecules or by the adaptive immune response when antibodies bind to antigens on the surface of invading molecules.

Anti-factor H antibody binds against factor H. Factor H is secreted by cells and expressed in the liver and in the plasma. Defects in factor H are associated with basal laminar drusen, complement factor H deficiency, and hemolytic uremic syndrome. Basal laminar drusens are accumulations of extracellular material that build up in the eye causing a starry appearance but not really interfering with vision. Complement factor H deficiency is an immunological disorder caused by a lack of factor H. Without it, the individual's immune system can start to attack its own cells in addition to any invading microorganisms. Anti-C3 antibody binds against the target compliment C3. Compliment C3 is secreted by cells and expressed in plasma. C3 plays a role in the activation of the complement system.

 
Product Number Title Applications Host Clonality
AC21-2636 Anti-Apolipoprotein J Antibody ELISA, WB Goat Polyclonal
AC21-2712 Anti-Apolipoprotein J Antibody ELISA, WB Goat Polyclonal
AC21-2732 Anti-Complement C3 Antibody ELISA Goat Polyclonal
AC21-2733 Anti-Complement C3 Antibody ELISA Goat Polyclonal
AC21-2993 Anti-C7 Antibody ELISA, WB Goat Polyclonal
AC21-0633-01 Anti-Mannan Binding Lectin Antibody (AMCA) ELISA, WB Goat Polyclonal
AC21-0633-02 Anti-Mannan Binding Lectin Antibody (AP) ELISA, WB Goat Polyclonal
AC21-0633-03 Anti-Mannan Binding Lectin Antibody (APC) ELISA, WB Goat Polyclonal
AC21-0633-04 Anti-Mannan Binding Lectin Antibody (APC-Cy5.5) ELISA, WB Goat Polyclonal
AC21-0633-05 Anti-Mannan Binding Lectin Antibody (APC-Cy7) ELISA, WB Goat Polyclonal
AC21-0633-06 Anti-Mannan Binding Lectin Antibody (Avidin) ELISA, WB Goat Polyclonal
AC21-0633-07 Anti-Mannan Binding Lectin Antibody (Biotin) ELISA, WB Goat Polyclonal