Questions? Feedback? powered by Olark live chat software

Circulatory

The circulatory system is an organ system responsible for transporting materials or nutrients throughout the body. The circulatory system is made up of numerous vessels that pass throughout the entire body along with the heart. Its main function is to transport chemicals (such as dissolved gases and waste products) to and/or from all points in an organism’s body. Organs of the circulatory system include the heart, the blood, and blood vessels.

Anti-alpha smooth muscle actin antibody binds against the target alpha smooth muscle actin. Actins are globular proteins that are the main framework of the thin filaments of muscle fibers. Actins are highly conserved proteins that are involved in many types of cell mobility. Alpha smooth muscle actin is an isoform of the typical smooth muscle cells. This actin is localized in the cytoplasm and the cytoskeleton. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6. Familial thoracic aortic aneurysm is an autosomal dominant form of large arterial disorder. The disease presents with a progressive breakdown of collagen, elastin, and smooth muscle in the wall of an artery, specifically the aorta. This caused the thoracic aorta to permanently dilate. Anti-Calponin antibody binds against calponin. Calponin functions as a thin-filament protein regulator/modulator of smooth muscle contraction. Calponin can bind to actin and inhibit the actomyosin Mg-ATPase activity. Actomyosin Mg-ATPase is involved in cardioprotection by maintaining intracellular calcium levels in ventricular myocytes that require ATP.

 
Product Number Title Applications Host Clonality
AC16-0055 Anti-VEGF Receptor 1 Antibody ELISA, WB, IHC(P), IP Rabbit Polyclonal
AC16-0063 Anti-Smoothelin Antibody WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-01 Anti-Smoothelin Antibody (AMCA) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-02 Anti-Smoothelin Antibody (AP) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-03 Anti-Smoothelin Antibody (APC) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-04 Anti-Smoothelin Antibody (APC-Cy5.5) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-05 Anti-Smoothelin Antibody (APC-Cy7) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-06 Anti-Smoothelin Antibody (Avidin) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-07 Anti-Smoothelin Antibody (Biotin) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-08 Anti-Smoothelin Antibody (BPE) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-09 Anti-Smoothelin Antibody (Cy3) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)
AC16-0063-10 Anti-Smoothelin Antibody (Cy5) WB, IHC(F), IHC(P), ICC, IF, FC, FUNC Mouse Monoclonal (R4A)