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Cellular Division

The cell cycle is a series of events in a cell that lead to the eventual division, duplication, and replication of the cell. This cell division occurs primarily in the nucleus where the DNA is housed. These processes include replication of DNA and mitosis or cell division. The replication of DNA has 3 distinct phases in which cells increase in size, DNA is duplicated, and a cell will continue to grow larger until it ultimately divides into two. These 3 phases are followed by the process of mitosis and an effective break or period of rest from division. The many processes that control the cell cycle are highly regulated and complex. Defects in the qualities of cell division can lead to cancer. Cancer ultimately results when cell regulation is out of control and normal cell growth and division patterns are not observed.

Anti-SET antibody binds against a target protein SET. SET is involved in apoptosis, transcription, nucleosome assembly, and histone binding. Both isoforms 1 and 2 of SET protein inhibit protein phosphatase and acetylation of histones and nucleosomes. The SET translocation protein mainly targets histone H4, and belongs to the nucleosome assembly protein (NAP) family. Anti-SET antibody functions in the cytoplasm, endoplasmic reticulum, and nucleus. SET is widely expressed in many tissues throughout the body. A chromosomal error involving the gene that codes for SET is sometimes responsible for causing acute undifferentiated leukemia. Acute undifferentiated leukemia, or stem cell leukemia, is characterized by acute myelogenous leukemia cells which are too immature to be classified. Anti- FOXP3 antibody detects a section of human FOXP3 protein. The FOXP3 protein is a transcription factor that controls certain immune responses and is thought to play a role in diabetes, infections (autoimmune and immunodeficiency), and anemia.

 
Product Number Title Applications Host Clonality
AC21-2645 Anti-CXCR2 Antibody ELISA, WB Goat Polyclonal
AC21-2715 Anti-PCNA Antibody ELISA, WB Goat Polyclonal
AC21-2716 Anti-PCNA Antibody ELISA, WB Goat Polyclonal
AC21-2717 Anti-Ki67 Antibody ELISA Goat Polyclonal
AC21-2718 Anti-Ki67 Antibody ELISA Goat Polyclonal
AC21-2825 Anti-Cdc6 Antibody ELISA, WB Goat Polyclonal
AC21-2860 Anti-CP110 Antibody ELISA, WB Goat Polyclonal
AC21-2889 Anti-PLK1 Antibody ELISA, WB Goat Polyclonal
AC21-2964 Anti-CSPP1 Antibody ELISA Goat Polyclonal
AC21-0023-01 Anti-Aurora A Antibody (AMCA) ELISA, WB Goat Polyclonal
AC21-0023-02 Anti-Aurora A Antibody (AP) ELISA, WB Goat Polyclonal
AC21-0023-03 Anti-Aurora A Antibody (APC) ELISA, WB Goat Polyclonal