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Cell Cycle

Cell cycle antibodies are involved in the cell division cycle of different types of cells. This cell division occurs primarily in the nucleus where the DNA is housed. These processes include replication of DNA and mitosis or cell division. The replication of DNA has 3 distinct phases in which cells will increase in size, DNA is duplicated, and a cell will continue to grow larger until it ultimately divides into two. These 3 phases are followed by the process of mitosis and an effective break or period of rest from division. The many processes that control the cell cycle are highly regulated and complex. Defects in the qualities of cell division can lead to cancer. Cancer ultimately results when cell regulation is out of control and normal cell growth and division patterns are not observed.

Cyclin dependent kinase, or Cdk adds a phosphate to a protein which ultimately switches a cell to start synthesizing DNA (S- phase) and to begin cell division (mitosis). The anti-CDK1 antibody plays a key role in this process. The 2nd isoform of this antibody is found in breast cancer tissues. The anti-alkaline phosphatase antibody (ALP) binds to ALP which removes the phosphate groups from the ends of both DNA and RNA prior to replication. In serum, ALP measurements can be abnormally high when the affected individual suffers from bone disease or liver disease since damaged tissues can release these enzymes into the blood.

 
Product Number Title Applications Host Clonality
AC16-0045 Anti-KLF4 Antibody ELISA, WB Rabbit Polyclonal
AC16-0047 Anti-p53 Antibody ELISA, WB, IHC(F), IHC(P) Rabbit Polyclonal
AC16-0072 Anti-BrdU Antibody WB, IHC(F), IHC(P), ICC, IF, FC Rat Monoclonal (BU1/75)
AC16-0045-01 Anti-KLF4 Antibody (AMCA) ELISA, WB Rabbit Polyclonal
AC16-0045-02 Anti-KLF4 Antibody (AP) ELISA, WB Rabbit Polyclonal
AC16-0045-03 Anti-KLF4 Antibody (APC) ELISA, WB Rabbit Polyclonal
AC16-0045-04 Anti-KLF4 Antibody (APC-Cy5.5) ELISA, WB Rabbit Polyclonal
AC16-0045-05 Anti-KLF4 Antibody (APC-Cy7) ELISA, WB Rabbit Polyclonal
AC16-0045-06 Anti-KLF4 Antibody (Avidin) ELISA, WB Rabbit Polyclonal
AC16-0045-07 Anti-KLF4 Antibody (Biotin) ELISA, WB Rabbit Polyclonal
AC16-0045-08 Anti-KLF4 Antibody (BPE) ELISA, WB Rabbit Polyclonal
AC16-0045-09 Anti-KLF4 Antibody (Cy3) ELISA, WB Rabbit Polyclonal
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Category
  1. Cell Cycle Inhibitors (1811)
  2. Cell Cycle Signaling (1000)
  3. Cellular Differentiation (1143)
  4. Cellular Division (2080)
  5. Cyclins (323)
Application
  1. ChIP (46)
  2. EIA (46)
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  4. FC (657)
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Conjugate
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  2. Alexa FluorÔö¼┬½ 647 (1)
  3. AMCA (286)
  4. AP (286)
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  6. APC-Cy5.5 (286)
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  8. Avidin (286)
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  22. PerCP-Cy5.5 (286)
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  25. RPE (286)
  26. Streptavidin (286)
Clonality
  1. Monoclonal (17(A17)) (23)
  2. Monoclonal (1E8-G6) (23)
  3. Monoclonal (3E2D10) (23)
  4. Monoclonal (3G3) (4)
  5. Monoclonal (46B11) (23)
  6. Monoclonal (5E6/2) (23)
  7. Monoclonal (6E1) (23)
  8. Monoclonal (9E10) (3)
  9. Monoclonal (9E11) (23)
  10. Monoclonal (AC8.3) (23)
  11. Monoclonal (AER314) (23)
  12. Monoclonal (Ali12-28) (23)
  13. Monoclonal (AN4.3) (23)
  14. Monoclonal (ARF4C6/4) (23)
  15. Monoclonal (BP53-12) (2)
  16. Monoclonal (BU1/75) (1)
  17. Monoclonal (Bu20a) (1)
  18. Monoclonal (CD1.1) (1)
  19. Monoclonal (cdc69H8/5) (23)
  20. Monoclonal (COL-1) (23)
  21. Monoclonal (Cor10G11/7) (23)
  22. Monoclonal (DCS118) (23)
  23. Monoclonal (DCS211.6) (23)
  24. Monoclonal (Ds-2) (1)
  25. Monoclonal (E23.1) (23)
  26. Monoclonal (E67.1) (23)
  27. Monoclonal (FAT-13D7/1) (23)
  28. Monoclonal (FP3.2 [FPS392]) (1)
  29. Monoclonal (GFR450) (23)
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  31. Monoclonal (H1+TS1) (23)
  32. Monoclonal (HCGb/54+ HCGb/459) (23)
  33. Monoclonal (Hs-14) (2)
  34. Monoclonal (Hs-8) (1)
  35. Monoclonal (J1D9) (23)
  36. Monoclonal (LST1/02) (1)
  37. Monoclonal (MoBu-1) (1)
  38. Monoclonal (P/T1) (23)
  39. Monoclonal (Pab1801) (23)
  40. Monoclonal (Pab1802) (23)
  41. Monoclonal (Pab240) (23)
  42. Monoclonal (POH-1) (1)
  43. Monoclonal (Rb1(1F8)) (23)
  44. Monoclonal (SPM166) (23)
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  47. Monoclonal (SPM354) (23)
  48. Monoclonal (SPM537) (23)
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  50. Monoclonal (SPM587) (23)
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  52. Monoclonal (SPM590) (23)
  53. Monoclonal (SX53G8) (23)
  54. Monoclonal (TC-113) (23)
  55. Monoclonal (TC-14) (23)
  56. Monoclonal (TC-19) (23)
  57. Monoclonal (VM452) (23)
  58. Monoclonal (WA-1) (1)
  59. Monoclonal (X29.2) (23)
  60. Monoclonal (Y100.4) (23)
  61. Monoclonal (zdd2) (23)
  62. Polyclonal (5557)
Host Species
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