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Allergy Antibodies

An allergy is an immune response to a typically harmless substance which may not bother the typical person or organism. Allergies are hypersensitivity disorders of the immune system. Typically, those who suffer from allergies are hypersensitive to more than one thing. The substances that cause allergies are called allergens. Allergic reactions can be picked up, are predictable, and fast acting. These reactions can range from minor to life threatening (anaphylaxis). Anaphylaxis is a severe allergic reaction that is rapid in onset and may cause death. Despite the severity of an allergic reaction, they are characterized by immune responses which involve a certain types of white blood cells called mast cells and basophils. These blood cells are excessively activated in response to the environmental allergen by allergy antibodies from the group labeled: immunoglobulin E. Immunotherapy involves the desensitization treatment of a person who suffers from allergies. Allergy antibodies are useful in the process by which affected individuals are vaccinated gradually with the allergen in hopes of progressively skewing the production of immunoglobulin G (IgG) antibodies which can block the excessive production of immunoglobulin E (IgE) antibodies seen in allergic individuals.

Histamine receptor 1 antibody binds against the histamine receptor protein. This receptor is a G-protein coupled receptor that mediates the contraction of smooth muscles, increases capillary permeability due to contraction of terminal venules, neurotransmission in the central nervous system, and catecholamine release from the adrenal medulla. Histamine receptor 1 belongs to the H1 subclass of histamine receptors and is found in peripheral tissues in the cell membrane. PDE4D antibody binds against the PDE4D target. PDE4D itself hydrolyzes cyclic adenosine monophosphate (cAMP). Cyclic adenosine monophosphate (cAMP) is the primary regulator of many significant physiological processes. PDE4D is found in many different tissues including skeletal muscle, placenta, brain, lung, kidney, and heart. It is found in the cytoplasm and membranes of cells. It plays a role in allergic reactions as well as other diseases. Defects or variations in PDE4D are thought to be associated with a person’s susceptibility to stroke.

 
621 products match WB
Product Number Title Applications Host Clonality
AC21-1082-01 Anti-TBC1D4 Antibody (AMCA) ELISA, WB, IHC Goat Polyclonal
AC21-1749-17 Anti-ORAI1 Antibody (PE-Cy7) ELISA, WB Goat Polyclonal
AC21-0286-01 Anti-CLLD8/SETDB2 Antibody (AMCA) ELISA, WB Goat Polyclonal
AC21-0780-17 Anti-Beta 2 Adrenergic Receptor Antibody (PE-Cy7) ELISA, WB Goat Polyclonal
AC21-1130-11 Anti-HRH1 Antibody (Cy5.5) ELISA, WB Goat Polyclonal
AC21-0707 Anti-ADAM33 Antibody ELISA, WB Goat Polyclonal
AC21-0563-11 Anti-FLAP Antibody (Cy5.5) ELISA, WB Goat Polyclonal
AC21-0864-05 Anti-TIM 3 Antibody (APC-Cy7) ELISA, WB Goat Polyclonal
AC21-1200-21 Anti-CD26 Antibody (RPE) ELISA, WB Goat Polyclonal
AC21-0704-21 Anti-DPP10 Antibody (RPE) ELISA, WB Goat Polyclonal
AC21-0988-15 Anti-5 Lipoxygenase Antibody (PE-Cy5) ELISA, WB Goat Polyclonal
AC21-1606-09 Anti-IRAKM Antibody (Cy3) ELISA, WB Goat Polyclonal